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Thalassemia

An inherited disease

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A Quick Tip by Sharrie

  • Jun 28, 2011
Other than being anemic, there is no backlash from this (inherited disorder of haemoglobin in the red blood cells) condition. As it is quite prevalent in the Asian population, it is of utmost importance to confirm if one has it or not when planning for pregnancy. If both parents carry traits of it, the child will be affected. Genetic counselling is needed in that case. Otherwise, no treatment is needed.



Thalassemia originated in the Mediterranean. The world Thalassa means sea (Mediterranean Sea) while anaemia means weak blood. Both are Greek words. To read more about this condition, click here. Most people won't know they carry Thalassemia unless they are tested mildly anemic or go for further testing. There are no outward symptoms and no special treatment, be it diet or medical is needed.

By the way, there's even a World Thalessemia Day! It falls on May 19, 2011 this year!

I suspect I'm a carrier though I haven't had it confirm by the doctor!
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June 28, 2011
Hmm....please don't go....don't go.....we want you to stay....
June 29, 2011
4 more list at best.

500 reviews, 1200 QT & 100 lists. I think I've overspent my time on leisure!!! I've got to get some real work done out there in the world :) Can't be lunch-ing everyday without any income to pay the bills! 
 
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Sharrie ()
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I'm a traveler at heart & have been nicknamed Travel Queen by friends & colleagues alike. Traveling has been my life passion for the last decade or so. As we enter a new decade, I'm excited … more
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Wiki

Thalassemia (also spelled thalassaemia) is an inherited autosomal recessive blood disease that originated in theMediterranean region. In thalassemia the genetic defect, which could be either mutation or deletion, results in reduced rate of synthesis or no synthesis of one of the globin chains that make up hemoglobin. This can cause the formation of abnormal hemoglobin molecules, thus causing anemia, the characteristic presenting symptom of the thalassemias.

Thalassemia is a quantitative problem of too few globins synthesized, whereas sickle-cell disease (a hemoglobinopathy) is a qualitative problem of synthesis of an incorrectly functioning globin. Thalassemias usually result in underproduction of normal globin proteins, often through mutations in regulatory genes. Hemoglobinopathies imply structural abnormalities in the globin proteins themselves.[1] The two conditions may overlap, however, since some conditions which cause abnormalities in globin proteins (hemoglobinopathy) also affect their production (thalassemia). Thus, some thalassemias are hemoglobinopathies, but most are not. Either or both of these conditions may cause anemia.

The two major forms of the disease, alpha- and beta- (see below), are prevalent in discrete geographical clusters around the world - probably associated with malarialendemicity in ancient times. Alpha is prevalent in peoples of Western African and South Asian descent. It ...

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