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Flowers for Algernon is a science fiction short story and subsequent novel written by Daniel Keyes. The short story, written in 1958 and first published in the April 1959 issue of The Magazine of Fantasy & Science Fiction, won the Hugo Award for Best Short Story in 1960. The novel was published in 1966 and was joint winner of that year's Nebula Award for Best Novel (with Babel-17).

The titular Algernon is a laboratory mouse who has undergone surgery to increase his intelligence by artificial means. The story is told as a series of progress reports written by Charlie, the first human test subject for the surgery, and touches upon many different ethical and moral themes such as the treatment of the mentally disabled.

Although the book has often been challenged for removal from libraries in the US and Canada, sometimes successfully, it is regularly taught in schools around the world and has been adapted numerous times for television, theatre, radio and as the Academy Award-winning film, Charly.

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