The Fairmont did a great job with this downtown Pittsburgh hotel that opened in March of 2009. Here are some of the highlights of why I wouldn't stay anywhere else while in the Burgh:
Location - It is perfectly centrally located in the heart of downtown with views of the river, adjacent to the Heinz Hall (concerts/shows), an extremely short walk to PNC Park (home of the Pirates), to Heinz Field (home of Steelers) and many restaurants, bars and retail..
Rooms - What you would expect from a Fairmont 2010 opening hotel, high quality through and through. Very nice furniture, comfortable bed, high end bathroom fixtures. I received a free suite upgrade which was huge, but imagine regular rooms are good size as well.
Amenities - Everything in the hotel is state of the art, featuring one of the nicest health clubs/gyms I have ever seen in a hotel, including a steam room and dry sauna. There is also a full spa.
Food/drinks - The lobby features Andy's, a lounge that has become a happening happy hour spot that serves casual fare. A full restaurant, Habitat, offers cuisine focused on local, sustainable ingredients. I did not end up making it to Habitat, so I can't shed any light there.
Cost - The two room, upgraded suite I had, with "river view" was $204/night. This was over MLK weekend in January, Steelers playoff game.
Quote - I'll leave you with this. The opposing team, Baltimore Ravens, were staying at the hotel while I was there. Heading from gym back to the room, i was greeted in elevator by six of the Ravens players. Talking about the hotel, one of them said, "This is the nicest hotel we've stayed at, the only other one maybe as nice was the Ritz Carlton in St Louis".