The program CCleaner (www.pirifrom.com/ccleaner) has long been a favorite for maintaining the health of Windows systems. It removes .tmp files, cache files, cookies, has a registry cleaner, and a tool kit for removing old software. The advantage of this tool is that it not only removes the program file but also any left over files in the registry or elsewhere.
CCleaner is safe and easy to use. It would be very difficult to do any real damage to your system with it. You could find you have removed cookies that are temporarily distracting because some web sites may not auto fill blocks for your email, name, or home web site. This means you may have to do this manually for a short time. That's a small price to pay for keeping tour system running "mean and lean".
Now Piriform has released in Beta a version for the Macintosh, too. I have been using the Windows version for years so was eager to try the Mac version. The interface and performance is nearly identical. Some features for Windows, such as the software deletion program are not on the Mac side. Perhaps when the final release version is available this will be corrected. Until then, there is Appcleaner.app (http://www.freemacsoft.net/).
Appcleaner removes applications and their associated files very quickly and effectively. I've also used it for several years and have never had any problem with it. It not only removes the application software but also any entries in the Library (a bit similar to Windows Registry) to leave your system with not useless files taking up space on your drive.
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About the reviewer
James Smith (slrman)
Retired bum, technical writer and fitness fanatic in João Pessoa, Brazil.
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CCleaner (formerly Crap Cleaner), developed by Piriform is a utility program used to clean potentially unwanted files and invalid Windows Registry entries from a computer. A public beta version for the Mac has been released.