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The Big Bang Theory is a situational comedy that premiered on CBS on September 24, 2007, which is created and executive produced by Chuck Lorre and Bill Prady. The series takes two male Caltech prodigies in their twenties, an experimental physicist (Leonard) and a theoretical physicist (Sheldon) and places them across the hall from the beautiful blonde intelligent waitress (Penny), who is aspiring to make it in show business. Despite the two physicists' genius, they experience trouble relating and interacting with others, especially women. Penny's personality contrasts with her geeky neighbors, leading to the shows comedic effect. The show is produced by Warner Brothers Television and Chuck Lorre Productions, starring Johnny Galecki, Jim Parsons, Kaley Cuoco, Simon Helberg, Kunal Nayys and Sara Gilbert.